A one-of-a-kind brain-imaging instrument in Hungary is advancing cutting-edge neuroscience research at Széchenyi István University. The NIRSport2 is the first brain-imaging device available in Hungary capable of displaying cortical activity in real time without spatial limitations.

Széchenyi István University conducts research aimed at promoting health across all social groups and age categories. Recently, the institution has expanded its technological resources with an innovative tool that enables experts to gain deeper insights into brain processes, contributing to advancements in healthcare and neuropsychology.

The brain-imaging device used at Széchenyi István University closely resembles a cap ensuring a completely comfortable experience for the wearer during operation. (Photo: András Adorján)

"The NIRSport2 system acquired by our University significantly expands the research opportunities of our Faculty of Health and Sports Sciences in fields that contribute to the well-being of humanity as a whole. Recently, experts from the Berlin-based health technology company NIRx visited our institution, providing our colleagues with a comprehensive introduction to the device’s operation and the necessary software applications. Its application will commence in numerous scientific projects, covering areas such as trauma research, cortical inhibition of primitive reflexes, attention disorders, the placebo effect, and age-related cognitive decline," stated Dr. Angéla Somogyi, Dean of the Faculty.

Dr Erzsébet Stephens-Sarlós, a sensorimotor trainer and researcher at the University, emphasized that this is the only mobile device of its kind in Hungary, capable of examining patients in real time while they are in motion. “Since the test subject is not tethered to a machine, we can measure the brain activity of multiple individuals simultaneously while they engage in various activities, such as playing chess, exercising, or attending a lesson,” she explained. According to Dr Stephens-Sarlós, the device has a remarkably broad range of applications, as it can be used in any case involving cortical function, given its ability to examine the cerebral cortex in its full thickness. 

“Over the years, I have traditionally examined more than 7,000 children, accumulating extensive experiential knowledge. Through the University, we are now involving the elderly population as well, aiming to achieve significant results in dementia prevention. With this device, we can obtain concrete data on the neurophysiological processes occurring in the nervous system, which may provide explanations and solutions for numerous issues,” she noted. As an example, she explained that in infancy, primitive reflexes essential for development are inhibited by neurotransmitters produced by a mature nervous system. The disappearance of these early reflexes signals that the nervous system has matured and is prepared for higher-level tasks. However, in old age, the level of gamma-aminobutyric acid (GABA), the inhibitory neurotransmitter responsible for this process, significantly declines, leading to the reactivation of primitive reflexes. These re-emerging reflexes serve as indicators of frontal release and are observed in nearly all forms of dementia, including Alzheimer’s disease, multiple sclerosis, Parkinson’s disease, and other neurological disorders such as schizophrenia. “When primitive reflexes reappear, we aim to identify which cortical regions exhibit reduced function and decreased activity. By studying this, we can determine specific exercises that can help voluntary movements regain control over lower-level involuntary movements,” she elaborated.

Dr Erzsébet Stephens-Sarlós is a sensorimotor trainer and researcher at Széchenyi István University. (Photo: András Adorján)

She emphasized that the time factor is of critical importance for both children and the elderly, as this knowledge enables targeted stimulation of the appropriate brain areas. “It makes a significant difference whether a young child struggling with difficulties experiences their first months at school positively or negatively, just as it matters how long an elderly person is able to maintain their independence. These are issues that affect society as a whole, and our research allows us to have a meaningful impact on them,” she stressed.

Széchenyi István University is also actively engaged in significant international projects in this field, collaborating with Dublin City University and Maynooth University in Ireland. The preparatory phase is nearing completion, and in September, joint dementia research will commence, from which experts anticipate substantial findings. The aim is to integrate these results into Irish healthcare practices, while discussions have already begun with the neurology department of Petz Hospital in Győr regarding potential applications in Hungary.

“The innovative approach of Széchenyi István University’s leadership has enabled us to work with state-of-the-art technology, facilitating internationally recognized research, publications, and the development of practical new methodologies. With these advancements, we can contribute to addressing attention disorders and helping children fully realize their potential. Additionally, we can support older adults in maintaining their physical and cognitive fitness for as long as possible and identify which areas of the nervous system need reinforcement to mitigate the effects of post-traumatic stress,” summarized Dr Stephens-Sarlós.